Different studies have detected close similarities in neuronal signaling pathways and functional regions of the brain. Alterations in the mobility pattern of larvae induced by known drugs have been observed to strongly support the zebrafish as a predictive model of neuroactivity in humans. Behavioral profiling in zebrafish reveals relationships between drugs and their targets and demonstrates a conserved vertebrate neuropharmacology.
Biobide has set up an assay to evaluate general behavioral alterations, based on responses to dark-light changes. The assay is performed under Good Laboratory Practice (GLP) environment.